LOCUS       IS26-blaLAP-2-qnrS1-IS26_unit10239 bp   DNA linear  BCT 03-OCT-2020
DEFINITION  Escherichia coli.
ACCESSION
VERSION
KEYWORDS    .
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; gamma subdivision; Enterobacteriaceae;
            Escherichia.
REFERENCE   1  (bases 1 to 10239)
  AUTHORS   Zhou,D.
  TITLE     Complete sequence of IS26-blaLAP-2-qnrS1-IS26 unit
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10239)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-OCT-2020) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            Beijing, Beijing 100071, China
FEATURES             Location/Qualifiers
     source          1..10239
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:562"
     mobile_element  1..10239
                     /gene="IS26\u2013blaLAP-2\u2013qnrS1\u2013IS26 unit"
                     /product="Putative resistance unit:
                     IS26\u2013blaLAP-2\u2013qnrS1\u2013IS26 unit"
     mobile_element  1..820
                     /gene="IS26"
                     /product="Insertion sequence: IS26"
     repeat_region   1..14
                     /gene="IRL_IS26"
                     /product="IS26 inverted repeat left"
     CDS             64..768
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="IS26 transposase"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDH
                     STIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTV
                     DFYLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDV
                     EHRQIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYY
                     GDPLGEMRLVSRVFEM"
     repeat_region   807..820
                     /gene="IRR_IS26"
                     /product="IS26 inverted repeat right"
     CDS             816..2192
                     /gene="fts1"
                     /codon_start=1
                     /transl_table=11
                     /product="Putative peptidoglycan synthetase Fts1#"
                     /translation="MPLRRTIQDNSDKEFLFLKKKSPLSLSRAVSQLHLPGISQKYNE
                     NRYYPLGEASASLIGVTGAENRGLSGIEQSFNTVLRKDFGVKKIRKNARGGVISVIQY
                     DAPETAPAIRLSIDSVLQYIVYSRLREGVEQHHAQSGAAVLVSVNTGEILAMASYPSF
                     NPNRFSGATSAEMRNVAINDSFEPGSTVKPFVILEGLRRHIISSSTLLDTRPFRVDGH
                     LIRDVGYWPALTPTGILQKSSDTGVSHIALAMPSDALVKTYSSFGLGKPTGLGLPGES
                     TGYFPFSRHRWADIERATFAFGYGLRVTPLQLARAYATLGACGVYHPLSVTRLSAPVY
                     GEQVADPKLADAVIRMMESDVLPGGSGVRAAVPGYRLAIKTGTAEKLGAGGKYDGGHI
                     TYTAGVAPASRPEVALVVVINNPKAGQHFGGSVAAPVFGQIIGPVLTRLKIAPDALRA
                     PVVHRQSG"
     CDS             2257..3114
                     /gene="blaLAP-2"
                     /codon_start=1
                     /transl_table=11
                     /product="Beta-lactamase LAP-2"
                     /translation="MKKIRLIIISLLAGMCTPALSTPVNVTDTIQSTEDHIKGRVGFT
                     EIDFLSGKVLSSHRREERFPMMSTFKVLLCGAILVRVDKGLEQLERRITYNKHDLDDY
                     SPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGPEGLTHFLRSTGDSYTRLD
                     RHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRKKLISWMQEDKVGGPLF
                     RSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITNTHSSMNELNEHIAG
                     IGDSVIKNW"
     mobile_element  complement(3684..4407)
                     /gene="truncated ISEcl2"
                     /product="Insertion sequence: truncated ISEcl2"
     misc_feature    complement(3684..3990)
                     /gene="truncated insB"
                     /product="Truncated ISEcl2 transposase InsB (pseudogene)"
     misc_feature    complement(3948..4316)
                     /gene="insA"
                     /product="ISEcl2 transposase InsA"
     repeat_region   complement(4366..4407)
                     /gene="IRL_ISEcl2"
                     /product="ISEcl2 inverted repeat left"
     CDS             4711..5367
                     /gene="qnrS1"
                     /codon_start=1
                     /transl_table=11
                     /product="Plasmid-mediated quinolone resistance protein"
                     /translation="METYNHTYRHHNFSHKDLSDLTFTACTFIRSDFRRANLRDTTFV
                     NCKFIEQGDIEGCHFDVADLRDASFQQCQLAMANFSNANCYGIEFRACDLKGANFSRT
                     NFAHQVSNRMYFCSAFISGCNLSYANMERVCLEKCELFENRWIGTNLAGASLKESDLS
                     RGVFSEDVWGQFSLQGANLCHAELDGLDPRKVDTSGIKIAAWQQELILEALGIVVYPD
                     "
     misc_feature    complement(5686..6123)
                     /gene="truncated tnpR"
                     /product="Truncated transposon resolvase"
     mobile_element  complement(6116..8966)
                     /gene="ISKpn19"
                     /product="Insertion sequence: ISKpn19"
     repeat_region   complement(6116..6141)
                     /gene="IRR_ISKpn19"
                     /product="ISKpn19 inverted repeat right"
     CDS             complement(6147..7538)
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="ISKpn19 transposase"
                     /translation="MQLTLQIVITDESGSSRTEELMTIQKSGETRNDIGLSVSESKLL
                     LNTVQQSVVQLQADEYTQHHIRCPHCLAARRIKGKQKIRYRTLFGVIPVSGLRVYRCR
                     CEESDTKTVSLLSDWAGDYSHPALKYIETRWASMISYEMTTRLLKDILPVGHSLNAST
                     VRNHLCQVAQRLDAEAEAHSGFLSGCPRDWGNLPRPGKPLVVGIDGGYVRDRDDKKRN
                     FEIIAGKSFSVGAPADTRRFGFVQKDDCHPERRLMTHLSAQGMQANQQIFFLSDGADN
                     LRDLQFGMYPESTHVLDWFHITMRLKVLMQYARGLLVSDPEAGSKVLALLESIKRYLW
                     HGNVVAALEHIDNCVMYCDDPELSYPSLKSLQKHLDEMYTYIRNNKMMIPNYGEMRRY
                     GEPVSTAFVESTINEVIARRMAKKQQMQWSRKGAHYLLQTRTAVLNNELQDKFVCWYP
                     GFQSDGKGPAMAA"
     CDS             complement(7575..8147)
                     /gene="orf573"
                     /codon_start=1
                     /transl_table=11
                     /product="Serine recombinase"
                     /translation="MQYAYIRVSSADQNTARQEEALSKAGFQPDKICVEHASAKDTNR
                     PGLQELLGQLRPGDTLLVHSIDRLCRNMSDMCAVTTRLRDQGVTLIFLKEQLTFSAGT
                     NNPMQELQLHMMSAFSQFERALLKERQADGIAAKKARGEKTGRPGADIKKIQEIDALR
                     SRGVRLRIACDHAGLGVSTYYKLRHQMNNQ"
     CDS             complement(8284..8874)
                     /gene="orf591"
                     /codon_start=1
                     /transl_table=11
                     /product="Hypothetical protein"
                     /translation="MKIYVIKIAVHGVSPMVWRRLRIAADTSLAALHFIFQIVQGWGD
                     DHLHQFHIYGKDYGISYEGGIGFVDNPFRVVIDDFAFDAGDRFTYEYNFFEHWLHDIR
                     VEAIYENSTLKAPFCISGHGMPGATAADEFDKTLAFLEAIVNADDETTVGEIRPFADD
                     LDAVRFNRHKINRQLSRLDLASPVLEPEVIWLGRRR"
     repeat_region   complement(8941..8966)
                     /gene="IRL_ISKpn19"
                     /product="ISKpn19 inverted repeat left"
     mobile_element  9420..10239
                     /gene="IS26"
                     /product="Insertion sequence: IS26"
     repeat_region   9420..9433
                     /gene="IRL_IS26"
                     /product="IS26 inverted repeat left"
     CDS             9483..10187
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="IS26 transposase"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDH
                     STIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTV
                     DFYLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDV
                     EHRQIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASAFYY
                     GDPLGEMRLVSRVFEM"
     repeat_region   10226..10239
                     /gene="IRR_IS26"
                     /product="IS26 inverted repeat right"
BASE COUNT     2487 a   2616 c   2556 g   2580 t
ORIGIN
        1 ggcactgttg caaatagtcg gtggtgataa acttatcatc cccttttgct gatggagctg
       61 cacatgaacc cattcaaagg ccggcatttt cagcgtgaca tcattctgtg ggccgtacgc
      121 tggtactgca aatacggcat cagttaccgt gagctgcagg agatgctggc tgaacgcgga
      181 gtgaatgtcg atcactccac gatttaccgc tgggttcagc gttatgcgcc tgaaatggaa
      241 aaacggctgc gctggtactg gcgtaaccct tccgatcttt gcccgtggca catggatgaa
      301 acctacgtga aggtcaatgg ccgctgggcg tatctgtacc gggccgtcga cagccggggc
      361 cgcactgtcg atttttatct ctcctcccgt cgtaacagca aagctgcata ccggtttctg
      421 ggtaaaatcc tcaacaacgt gaagaagtgg cagatcccgc gattcatcaa cacggataaa
      481 gcgcccgcct atggtcgcgc gcttgctctg ctcaaacgcg aaggccggtg cccgtctgac
      541 gttgaacacc gacagattaa gtaccggaac aacgtgattg aatgcgatca tggcaaactg
      601 aaacggataa tcggcgccac gctgggattt aaatccatga agacggctta cgccaccatc
      661 aaaggtattg aggtgatgcg tgcactacgc aaaggccagg cctcagcatt ttattatggt
      721 gatcccctgg gcgaaatgcg cctggtaagc agagtttttg aaatgtaagg cctttgaata
      781 agacaaaagg ctgcctcatc gctaactttg caacagtgcc acttcgcaga actattcaag
      841 ataattcgga caaggaattc ctgtttctga agaaaaagtc gcccctgtca ttgtccaggg
      901 ccgtgtcaca gctgcatctg ccgggcataa gtcagaaata caatgaaaat cgctactatc
      961 cgctgggtga ggcatcagcc tcgctcattg gtgtgaccgg tgccgaaaat agagggctga
     1021 gtggtattga gcagagcttt aacaccgttc tgagaaagga cttcggggtg aaaaaaatac
     1081 gcaaaaacgc cagggggggc gtcatcagcg tgatccagta tgacgctccg gaaactgcac
     1141 cggcgatcag gctgagtatt gacagtgtgc ttcagtatat tgtttacagc cggttaaggg
     1201 agggggtcga gcaacatcac gcccagtcag gcgctgcggt gcttgtcagc gtaaacaccg
     1261 gcgaaattct ggctatggca tcctatccgt cgtttaatcc caaccgtttt tccggtgcca
     1321 cttccgctga aatgcgtaac gtggcgatta atgacagctt tgagccgggt tcaacggtta
     1381 aacccttcgt cattcttgaa ggcctgcgcc gccatattat cagcagcagc acgcttcttg
     1441 acacaaggcc gttcagggtt gacggccatc ttatccggga cgtgggatac tggccggcgc
     1501 tgacgccgac cggcatactt cagaaatcca gtgataccgg agtttcacat attgccctgg
     1561 cgatgccttc ggatgcgctg gtaaaaacgt attcatcctt cgggctggga aaaccgacag
     1621 ggctgggcct tcccggtgaa agtactggtt actttccgtt cagtcgccat cgatgggctg
     1681 atattgagcg cgccaccttc gcttttggct acggcctccg ggtaaccccg ctccagttag
     1741 ccagagccta tgccactctc ggggcctgtg gcgtttatca tccgttatcc gttacacggt
     1801 tatccgcgcc ggtgtacggt gagcaggtgg cggacccgaa gcttgccgat gctgtaatca
     1861 gaatgatgga aagtgatgtg ttacccggcg gaagtggcgt aagggcagct gtaccgggct
     1921 accgtctggc aataaaaacc ggaaccgcag agaagttagg tgccggtgga aaatatgacg
     1981 gggggcatat tacctatacg gcaggcgtcg cgccggcgag ccgtcctgaa gtggcactgg
     2041 ttgtggttat taacaatccc aaagcgggac agcattttgg tggctcagtg gcggcgcctg
     2101 tcttcggcca gattatcggt ccggtgctta cccggctgaa gattgcaccg gatgctttac
     2161 gtgctccggt ggtacaccga cagtccggct gaacagagcc tgtttactca ttatttatct
     2221 attattactt aacttaattt taaaaaggat attaatatga aaaagatccg ccttattata
     2281 atctctttac tggctggaat gtgtactcca gcattatcta caccagtcaa tgttactgat
     2341 acaatacaaa gcacagaaga ccatatcaaa ggtcgggttg gttttactga aatagacttt
     2401 ttatccggga aggttctgag tagtcatcgc cgtgaagaac gttttcctat gatgagcaca
     2461 ttcaaagttt tgttatgtgg agcaatatta gtacgtgttg ataaagggct tgaacaactt
     2521 gaacgccgaa ttacctataa taagcatgac ctggacgact attctccact aaccagtcag
     2581 cacattgcag atggaatgac ggtttctgag ttatgcaatg ctgccattac caccagtgat
     2641 aacactgctg caaatttatt gctatcaact attggcgggc cggagggatt aactcatttt
     2701 ctgcgtagca ctggtgatag ttatacaagg cttgatcgac acgaacccag ccttaatgag
     2761 gcgaagcctg gcgatgagcg tgataccacc actccggcag cgatggctca aacgctacaa
     2821 aaattgttaa acgaaagtgt acttacagaa aaatctcgaa aaaaattaat aagctggatg
     2881 caggaagata aagtcggcgg gcctctgttc cgctctgtac tgccagctgg ctggatgata
     2941 gcggataaaa caggagcagg tgatcacgga tctcggggca tcgttgcact gttgggcccc
     3001 ggaggcaagc catctcgtat agtagtcctg tatattacaa atactcattc atctatgaat
     3061 gaactcaacg agcatattgc agggatcgga gattcagtaa ttaagaactg gtaatatatt
     3121 tacagtggat ttgaccctat atatccagac gtttttgctc tcttacggtt gcgataactt
     3181 cctgcgtata tattcccgtg gtgagcgata tcccagtgca ctatgcggat gatgttcgtt
     3241 gtaatgactg aacgccaccg ccagattcat caccgctgcc tcgctgtccg gtttcggcat
     3301 gatgctgatg tagtcccgtt ttatcgtcat cacgaagctt tctgctatgc cattgctttc
     3361 cgggcttcgc actgctgtcg tacaaggctc cagtcccagc aaccgggcga acgccggcac
     3421 tgttggcaac tgccttccga agcgtttttc caccgcaccc agcatgacat cctgcaccgt
     3481 ttctttgtca tagcctccgg tgctcgctgc ccagtcaatg atctccctgt cgcagcagtc
     3541 ctgcgcgaag gtcacccgca gcttttcgcc attatcacag cggaactcaa agccatctga
     3601 gcaccagcgc cggttacttt ccgctactgc tacgcgcccc ttatgggccc gcttacggca
     3661 aggatcagcg ggtttacgtt caagaagcag attatgcgtt ctcataatgc gatacacccg
     3721 ctttgcatta accacaggca ggccgtcccg ctctgactcc cgtcgcagca gcgcccacac
     3781 acggcgataa ccatacgtcg gcaggtcagc caccgccatg tttatccggg acaatacggt
     3841 ggtatcgtca gaacggggct gccgtctgcg atcctgtcag tcagatggcc ggtgaacccg
     3901 aatgctcaac tgcgcacgcg acacgccaag acttctgcaa acgtcgctta ttcgtcgttc
     3961 ccaggcaacg agggcgcatg cgcaatccat ttttttgccc ggccgaactc cacggcctct
     4021 ttgagtatct cggcttccat cgtctttttg cccagaaggc gctggagttc gcgaatttgc
     4081 ttattggcgg cagcgagttc ggaggccggc accacttcct cgcccgatgc aacagccgtc
     4141 agtgaaccgt cttaatattg cttgcgccat ttgaatatct ggtttgcatt gatgccatgc
     4201 aggcgcgcga catgagacac ggtcataccg ggctccatag tctgctgaat aatggcaatt
     4261 ttttcctgcg gtgtacgacg ccgacgccgc tcaggtcctg ataacacttc aaccatctta
     4321 tcgttctgac tggtattaaa catagttcca agactacctc ttattttaag agagtcgaag
     4381 tgtctggtga tctatggggc cagtctagcc ctcttccaag tgtagggaga tatagtcaaa
     4441 gtttgcttct ccgccgatga gtccgccctg cgtcggatag tccgattttt taccggcgaa
     4501 gcacggctct cctaacccta tctaaagcga ataacttttt tcaacagggc cgcgtgccaa
     4561 tgcaagagcg ataggcgctc tacgcgccaa tttgaccact taaaacaggt aaattgaggg
     4621 gttgtaatgt gttgatgtaa caggctttta ttttaatgtc ttggcatatg tataatggta
     4681 gtctagccct cctttcaaca aggagtactc atggaaacct acaatcatac atatcggcac
     4741 cacaactttt cacataaaga cttaagtgat ctcaccttca ccgcttgcac attcattcgc
     4801 agcgactttc gacgtgctaa cttgcgtgat acgacattcg tcaactgcaa gttcattgaa
     4861 cagggtgata tcgaaggctg ccactttgat gtcgcagatc ttcgtgatgc aagtttccaa
     4921 caatgccaac ttgcgatggc aaacttcagt aatgccaatt gctacggtat agagttccgt
     4981 gcgtgtgatt taaaaggtgc caacttttcc cgaacaaact ttgcccatca agtgagtaat
     5041 cgtatgtact tttgctcagc atttatttct ggatgtaatc tttcctatgc caatatggag
     5101 agggtttgtt tagaaaaatg tgagttgttt gaaaatcgct ggataggaac gaacctagcg
     5161 ggtgcatcac tgaaagagtc agacttaagt cgaggtgttt tttccgaaga tgtctggggg
     5221 caatttagcc tacagggtgc caatttatgc cacgccgaac tcgacggttt agatccccgc
     5281 aaagtcgata catcaggtat caaaattgca gcctggcagc aagaactgat tctcgaagca
     5341 ctgggtattg ttgtttatcc tgactaattg ctttgatgtg tgattttaaa cgctcaaatt
     5401 tataaaacga ataatattgt caaccttgca ataatagaca tagggacaac catgtataaa
     5461 tttttaccct caggcgtctt cacaatagag ccatatagca gtgggtcact tagtgggctt
     5521 aatttttcca ttaaagataa tattaatatt gctcagtata aaacatcata tggtagccca
     5581 tcttggcaag taaacataag gctgccattt ataaggcact gttgcaaaaa tgtggaggtg
     5641 ataggggtac tacgccggaa ccccagattt ttccgtccgt tcaaattatc cacggttgag
     5701 cagcttgatc ccgtccgccc gcagttgacc aacaggggaa atatgcctgt acaaagtttg
     5761 ccgggttatc ccaagttcct ggcatagcgt actgaccttt gtttctgatt gtcccattga
     5821 tgccattgcc agtcgcagtt tgactggcgt cattttataa ggtcggccgc cgttccgccc
     5881 acgggctctt gctgatgcca gacctgcagt cgttctttca gcaatcagtt cgcgctcaaa
     5941 ctccgccagt gcggcaaaga taccgaagac aagcttgcca gcggccgttg ttgtgtcgat
     6001 agtcgccccg tgaccggtca gcactttcag accggtcccc ctcgcggtca ggtcgtgcac
     6061 tgtattaatg agatgacgaa gatcacgacc gaggcggtcc agcttccata cgaccgagag
     6121 cataaaaaat attggggcag cgtgagctat gctgccatcg ctggtccctt cccgtcactt
     6181 tgaaaacccg gataccagca gacaaattta tcctgcagtt cgttattcaa aacggcggtc
     6241 cgggtctgta acaaataatg agcccctttt ctgctccact gcatctgctg ctttttggcc
     6301 attcgtctgg cgatcacttc attgatcgtg gattccacaa acgcggttga taccggctct
     6361 ccgtaccgac gcatttcgcc gtagtttggg atcatcatct tattattccg gatgtaggta
     6421 tacatttcat ccagatgttt ttgcagggat ttcaggctag gatagctgag ttcagggtca
     6481 tcgcaataca taacgcaatt atcaatatgt tccagcgcag cgacaacatt gccatgccag
     6541 agatatcgtt taatgctttc cagcagtgcc agaactttac tccccgcctc tggatctgat
     6601 accagcagtc cccgggcata ttgcatgagc accttcagcc tcatggtgat atgaaaccag
     6661 tccagcacat gcgttgactc agggtacata ccgaactgga ggtccctgag attatccgcg
     6721 ccgtcggaca gaaaaaatat ctgctggttg gcctgcattc cctgcgctga aaggtgggtc
     6781 atgagcctgc gttccggatg acagtcatcc ttctgaacaa aaccgaagcg gcgggtgtca
     6841 gcaggcgcac caacggaaaa agacttcccg gcaataattt caaaattacg ctttttgtca
     6901 tcccgatcgc gaacataacc accatctata cccaccacaa gcggttttcc tggcctgggc
     6961 aggttccccc agtcgcgggg gcagccggaa agaaaacctg aatgagcttc agcctcagcg
     7021 tcaagacgct gcgccacctg gcataaatga ttcctcaccg ttgaggcatt caggctgtgg
     7081 cccaccggca gaatatcttt cagcagacga gtcgtcattt cataggagat catcgaggcc
     7141 cagcgggttt caatatattt cagtgccggg tgagaataat cgccggccca gtcgctgagc
     7201 aaactgactg tctttgtatc actctcttca caacggcacc ggtacacccg aagcccggat
     7261 accggaataa cgccaaacag cgtccggtac cgtattttct gtttgccttt gattctgcgc
     7321 gcagcaaggc agtgagggca ccggatatgg tgttgagtat attcgtctgc ctgcagctgg
     7381 accaccgact gctggaccgt attcagcaac agcttggatt ctgacaccga taatccgatg
     7441 tcgttccggg tctcccctga tttctggatt gtcatcagtt cctccgttcg actggagcct
     7501 gattcatcgg tgatgactat ctggagcgtc agttgcatca ttgcctcctg ctgtggtgga
     7561 tgactatctc ccggctactg gttgttcatc tggtgacgaa gcttataata tgtggaaacg
     7621 ccaaggcccg catggtcgca ggcgatcctg agcctgaccc ctctgcttct gagtgcgtca
     7681 atttcctgga tctttttgat atcggcgccg gggcgccctg ttttttcacc ccgtgctttt
     7741 ttcgcggcga tgccgtcggc ctgcctttcc ttcagtaagg ctcgttcaaa ctggctgaat
     7801 gccgacatca tgtgcagctg cagttcctgc atcggattgt ttgtgccggc gctgaacgtc
     7861 agctgctctt tcagaaaaat aagggtaacg ccctggtcac gaagccgggt ggtgacagcg
     7921 cacatatccg acatattccg gcaaaggcga tcgatggaat gaaccagaag cgtatcacca
     7981 gggcgtaatt gccccaggag ttcctgtaac cccgggcggt ttgtgtcctt cgcgctggca
     8041 tgctcaacac aaattttatc aggctgaaaa cccgcctttg acaatgcctc ttcctgacgg
     8101 gccgtattct gatcggccga gcttaccctg atgtaggcat attgcacgca aaacctccgg
     8161 aaggtcttta aacatcatag agatttaaag aataatccat aaacactgat ttagggaggt
     8221 ttatagacat tttttcgggg atctgagagg catgctgaaa acgtatacct ttatagacat
     8281 cagtcagcga cgacggccca gccagataac ttcaggctcc agtaccggag atgcaaggtc
     8341 gagcctgctc agttgccggt tgattttgtg gcggttgaac ctgacagcat ccaggtcgtc
     8401 agcaaaaggg cggatctcgc cgaccgttgt ttcatcatcc gcattaacga tagcttcaag
     8461 aaacgccagg gttttatcga actcatccgc agctgtggct ccgggcatac catggccgct
     8521 tatacaaaac ggcgctttca gcgtagagtt ttcataaatg gcctcaacac gaatgtcatg
     8581 aagccagtgc tcaaagaaat tgtattcata ggtaaagcga tcgccagcat caaaagcaaa
     8641 atcatcaatc acgacccgga acggattatc gacaaaaccg atgcctcctt cgtaggagat
     8701 accgtaatct ttgccataaa tgtgaaattg atggagatgg tcgtcccccc agccctgcac
     8761 tatctggaaa atgaagtgaa gcgcggccag tgacgtgtcg gcagcaattc tcagccgacg
     8821 ccagaccatc ggactgactc catgaactgc tattttgatg acgtagatct tcatagtcag
     8881 caggtattgt tatgaaatga tggtggttat tttaacccct gtagatggca tcattcgatg
     8941 gctgccccga ggtttttcat gctctcgcct atatggggtc tgaggtccaa ccatgcgaaa
     9001 aaccacgtta agaaagcaac cttctgaaaa ggcgacgttt atcagttttt tttccggcca
     9061 taaagggggc ggaaattatt ccctgcacgg gtattcgcaa ggatttcggt agtgctctgg
     9121 ctctgccccc cataacctgg cggacagagc atgattggga aagcggtacc ctcacggcag
     9181 aaacgattga cgcaggctat atttctatta ttctggaaat atagataaag gaggtattat
     9241 ggatttaaac actgctgcaa acgcacttcg agaactgggc cacccgacac gtctcagcat
     9301 ataccgggag ctggtcaggg cgggtcatga aggcctgccg gttggcgaac tgcagaagca
     9361 ccttgagatt cctgcctcca cgctcagcca tcatctttca gcgctgatat ccgctggacg
     9421 gcactgttgc aaatagtcgg tggtgataaa cttatcatcc ccttttgctg atggagctgc
     9481 acatgaaccc attcaaaggc cggcattttc agcgtgacat cattctgtgg gccgtacgct
     9541 ggtactgcaa atacggcatc agttaccgtg agctgcagga gatgctggct gaacgcggag
     9601 tgaatgtcga tcactccacg atttaccgct gggttcagcg ttatgcgcct gaaatggaaa
     9661 aacggctgcg ctggtactgg cgtaaccctt ccgatctttg cccgtggcac atggatgaaa
     9721 cctacgtgaa ggtcaatggc cgctgggcgt atctgtaccg ggccgtcgac agccggggcc
     9781 gcactgtcga tttttatctc tcctcccgtc gtaacagcaa agctgcatac cggtttctgg
     9841 gtaaaatcct caacaacgtg aagaagtggc agatcccgcg attcatcaac acggataaag
     9901 cgcccgccta tggtcgcgcg cttgctctgc tcaaacgcga aggccggtgc ccgtctgacg
     9961 ttgaacaccg acagattaag taccggaaca acgtgattga atgcgatcat ggcaaactga
    10021 aacggataat cggcgccacg ctgggattta aatccatgaa gacggcttac gccaccatca
    10081 aaggtattga ggtgatgcgt gcactacgca aaggccaggc ctcagcattt tattatggtg
    10141 atcccctggg cgaaatgcgc ctggtaagca gagtttttga aatgtaaggc ctttgaataa
    10201 gacaaaaggc tgcctcatcg ctaactttgc aacagtgcc
//
